An Opto-thermocapillary Cell Manipulator

نویسندگان

  • Wenqi Hu
  • Qihui Fan
  • Kelly S. Ishii
  • Aaron T. Ohta
چکیده

Single yeast cells in an agarose solution were patterned using the optically controlled thermocapillary flow surrounding a vapor bubble in the solution. After cell patterning, the agarose solution was gelled, and the cells were able to grow in this 3D biocompatible scaffold. Of the 12 cells in the initial pattern, 11 underwent multiple cell divisions during culturing for nine hours. This opto-thermocapillary manipulation provides a unique, cell-friendly method of patterning for cell and tissue cultures and associated research.

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تاریخ انتشار 2012